Title: Adipose-derived Mesenchymal Stem Cell Growth Factor and Cytokine Stability
Authors: Ho MR, RA Soriano, Vo DH, Vo ALY, Torfi H
Abstract
As cell-based therapies progress, adult stem cells hold a high level of interest field of regenerative medicine. Adipose-derived mesenchymal stem cells (ADSCs) are specifically being targeted as a viable autologous cell population in therapeutics due their relative abundance and ease of harvest. ADSCs cultured in vitro secrete signaling proteins including cytokines and growth factors which have demonstrated diverse regenerative capabilities when topically applied to the epidermis. As a result, cytokines and growth factors are incorporated into various topical cosmetic products. One major concern regarding the use of cytokines and growth factors in cosmetic products is the sensitivity of these proteins to environmental changes. The primary purpose of this study is to present preliminary data regarding the maintained integrity of cytokines and growth factors in cosmetic serum.
Keywords: cytokines, growth factors, adipose-derived stem cells, protein integrity
